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Transderma O Optimal Booster Serum

Size: 1oz
Transderma O is a cellular energizing serum featuring an optimized formulation of PQQ, B vitamins, and other select ingredients essential to skin’s cellular vitality. This new optimal booster serum offers focused support for the proper function of the mitochondria in skin cells. Transderma O’s specially balanced blend targets all layers of the skin for energizing cellular renewal. Transderma O is suitable for all skin types and is especially suitable for mature skin. Like all products in the Truth In Aging store, it has been tested by the community so that you can trust that it works.

Reviewed by Marta
When Scandinavian skincare company, Transderma, approached Truth In Aging to review their products, we asked (as we always do) for a full list of ingredients. What came back were lists of active ingredients. We pushed back, demanding a full list – including water, preservatives and anything else. “Our products don’t have water or preservatives”, was the response. I was immediately intrigued. Transderma was unlike any skincare line I had encountered.

Transderma formulates minimally with the focus on high performing actives. They are not diluted by water, nor compromised by chemical stabilizers, nor undermined by harsh preservatives. Well, any preservatives for that matter (an approach that is possible by avoiding water). For my test, I chose the most complex of the five serums,Transderma O Optimal Booster Serum.

There are but eight ingredients in Transderma O and seven of them are actives, including three forms of vitamin B, vitamin C and creatine (a cell signaler that is produced naturally in the body by amino acids). The most interesting is pyrroloquinoline quinone (PQQ), an ingredient that impacts mitochondria, the source of energy in our cells and critical to the aging process.

I did a deep dive into PQQ that you can read here. To summarize here, it is a small quinone molecule that is a REDOX agent, that is to say capable of reducing oxidants (an antioxidant effect). What has got scientists excited about PPQ is its ability to actually replenish mitochondria (a useful thing since they decrease with age). It also improves dry skin by inhibiting transepidermal water loss (TEWL).

Transderma O is one of the best products that I have ever used. Within a week, the texture of my face was visibly smoother. A week later, two weeks into my test, the skin on my neck was smoother. My cheeks felt and looked firmer. Five weeks into using Transderma O, the deeper lines on my forehead are more shallow.

The results are impressive and are corroborated by our other tester Emily, who was as astonished as me to find a serum that is almost 100% actives. As she noted in her review, given its targeted focus on cell health and recovery, Transderma O plays a very specific role in the skincare roster.
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$ 175.00
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Our Take

Truth in Aging recently gave me the chance to try an exceptional product.  Transderma is a focused and fascinating line of vitamin-rich and very targeted serums produced by a Swedish company called ProBios Laboratories, Inc.  My choice among the five-serum lineup was the O Optimal Booster... read more

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3 Reviews
  • Sheena

    (5 out of 5)

    I think this serum should be designated a gamechanger and I really wasn't expecting to say this. I thought it would be an interesting experiment but become it's a fixture. I find this serum hydrating, plumping and really calming and my skin simply looks younger and glowy when I use it for a few days in a row. It also calms the rosacea on my left cheek. It plays nicely with everything else I use - no greasiness, tackiness or pilling and it absorbs well. You're meant to use it as the first layer but the other night I was in a hurry before going out and smeared a pump over my face for a quick refresh and I felt as good as if I had put on makeup, because it just made my skin glow in a wholesome kind of way. I'm halfway through my first bottle which has lasted a couple of months so far with morning use only most days. It won't be my last bottle. Absolutely recommended and please don't stop stocking it!

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  • Sabrina

    (5 out of 5)

    O M G. This product is pure magic. I'm in my mid-to-late 30's, just finished having back to back babies, and all of a sudden I looked up in the mirror and was seeing large pores, dullness...I tried clean and not so clean products, looking for something. I never seemed to find anything that worked. I honestly didn't know what to expect with Transderma O but it's a game changer. Within a day or 2 (it's incredible how fast it worked), my skin completely changed. The pores have gone away, my face feels youthful, glowy. I have normal to dry skin, super sensitive, I suffer from ezcema around my lips and under my eye recently. Transderma O is incredible. I wish I could buy it for everyone I know. It's incredible. It's also helped to eliminate and simplify my routine. I just cleanse and use this serum and that's it. I don't feel like I need to do anything else. When I bought this, I got a sample kit of the other serums on this line and from time to time use the Transderma M (which is the moisturizing serum and what they rec to put on top instead of a moisturizer). I'm a fan of that too. I can't say anything negative about this product. It's expensive, but there's a lot in the product. I'm super happy and would 100% rec. Just do it! It's amazing!

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  • Emily

    (5 out of 5)

    I like everything about it, starting with the simple and attractive packaging (those Swedes). It’s an easily dispensed, clear (orange tinted) serum, perhaps due to the vitamin C, with a just slightly viscous feel on the skin; it spreads smoothly and absorbs quickly (the instructions do say to give it a couple of minutes before applying anything else). As the name implies, Transderma calls its products “deep absorbing.” And most importantly, my face and neck love it, and both appear and feel notably smoother, firmer, plumper, and very nicely moisturized. Given its targeted focus on cell health and recovery, plays a very specific role in the skincare roster and is worth including as a regular part of my regimen.

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  • Daniel Standard

    July 23, 2018

    Daniel Standard

    I have to be honest. I have not heard about PQQ being able to be absorbed through a serum. I know that to date most PQQ supplementation has been through pills, drinks, etc. Even at this price, can you really put a price on slowing aging? We will hear much much more about PQQ as we go forward. I am suprised PQQ hasn't been more popular. Don't get me wrong, on many fronts it is well known, but you see only a few brands in major health chains. With the ability to reproduce mitochondria, I expect in the years to come, we hear a LOT more about.

  • Karen

    June 20, 2018


    to rich for my pocket book

  • 1 2-propanediol
  • L-ascorbic acid
  • niacinamide (vitamin B3)
  • creatine
  • pyridoxine cylic phosphate (vitamin B6)
  • kinetin
  • pyrroloquinoline quinone (PQQ) disodium salt
  • biotin (vitamin B7)

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