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E'shee Clinical Esthetic Elixir of Life KI Therapy Serum

E'shee Clinical Esthetic Elixir of Life KI Therapy Serum

Size: 0.3 fl oz (10 ml)

E'shee Clinical Esthetic Elixir of Life KI Therapy Serum is the brand's most potent formula and works to rejuvenate damaged or aging skin while reducing deep wrinkles and improving moisture retention. This product activates the body's own stem cells to repair damaged tissue, reinvigorating damaged skin and restoring its vitality. Try this serum and see for yourself why Marta raves that within weeks of using E'shee Elixir of Life KI Therapy Serum, “my skin was looking even plumper, firmer and smoother.”

In this formula, E’shee combines growth factors (FGF 1 peptide) and Far Infrared Ceramic Powder (cFIR) to firm skin, increase volume, smooth texture, reduce redness caused by rosacea and repair broken capillaries. Additionally, they’ve included wholesome and nourishing botanicals like witch hazel, panax ginseng, chamomile, licorice and calendula to further prevent free radical damage and refresh the skin.

TIA Review by Marta:
E'shee Clinical Esthetic Elixir of Life KI Therapy Serum is having astonishing results on my skin. I am now on my second bottle and continue to be impressed (and grateful) for the effect on skin smoothness, tone and even on stubborn lines. Even my esthetician commented! E'shee has done it again.

One of the key actives is Far Infrared Ceramic Powder. It is also known as cFIR and in Asia, especially in Japan, it is regarded as a life-giving miracle worker that is actually woven into fabric. Far infrared waves are the longest rays in the light spectrum and easily absorbed by the body to a depth of up to 3 inches. There they can do useful things. Wound healing being one of them. Findings also revealed greater collagen regeneration and infiltration of fibroblasts that expressed transforming growth factor-(TGF-1).

E'shee KI Therapy also has the brand's signature FGF peptides, which are in the words of E'shee's founder, Nataly Giter, the basic building blocks of any fibrous tissue in human body. There is also a good handful of botanicals: witch hazel, panax ginseng, chamomile, licorice, epilobium angustifolium (willowherb and an anti-irritant as well as a source of vitamin C) and calendula. Interestingly, there is also glutamic acid, a precursor to GABA, a neuro-transmitter.

E'shee doesn't formulate for purists and there are all the usual suspects in the preservative department. I must say, though, that I am willingly turning a blind eye to them since KI works so consistently well for me.

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$ 189.00
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Our Take

E’shee KI Therapy Serum - Elixir of Life ($189 in the shop) is having astonishing results on my skin. I started to use it after I finished my bottle of AQ serum and so, it has to be said, my skin was looking good to start with. But within two to three weeks my skin was looking even plumper, firmer... read more

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23 Reviews
  • Jessica

    (5 out of 5)

    I just had my bad my big SIX-0 birthday--a rather low-key affair. However, in the last year, I've noticed a ssubtle "aging" of my face despite use of all of my great TIA purchases and use. So, I started paring down tmy product use to what seemed to be the most effective products for my skin. My thought: perhaps I was not giving my "top performers" a chance to really penetrate my skin.

    I ALSO consulted Marta who was extremely kind enough to respond the same day; she suggested Eshee's Clinical Esthetic Elixir of Life KI Therapy Serum. The price tag had me a bit stumped, but I'd already decided to eliminate several products that seemed to be costing me more than I wanted to spend. So, I jumpted in during one of Marta;'s relatively rare E'shee sales that providentially happened a few days later and bought TWO bottles of this 'liquid gold' without even trying ONE! I had a lot of faith in this E'shee product since I am already a total Eshee AQ Gene Therapy eye cream convert!.

    To add, I've been EXTREMELY ill for about four months in bed and have not partaken in my previously consistent twice daily skin care regimen. It's only been in the last weej or so that I am able to get out of bed for short periods of time and restart a very pared down daily skin care ... My skin has definitely taken a beating and besides being ill, I LOOKED sick and the many small wrinkles I'd finally lost with assiduous daily care...had returned. Within a week of using this product, I am ALMOST back to my pre-surgery/illness face. AND, I've not had the ability to stand or sit long enough to resume my previous use of Marta's Truth Vitality Lux Renew. which has been a big part of my daily skin care.

    I'd say that this product, DESPITE it's small amount for a large price tag....has made ALL THE DIFFERENCE. I plan to keep BOTH of these E'shee products in my regimen. DEFINITELY 5 stars!

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  • Tena

    (5 out of 5)

    AMAZING! I would proclaim this - the MIRACLE product. In just one week the wrinkles around my eyes literally disappeared. I don't have them any more. I know that it is not permanent and wrinkles will probably come back as soon as I stop using this product, but I'm amazed that serum can smooth the skin.. I didn't like alpha&omega eye cream by the same brand, but this serum really delivers results. I still can not believe that this is possible and I am thrilled that this product doesn't contain silicone which only masks the problems of the skin. This serum works better for me than Cellular Repair Serum by the same brand. Amazing stuff! Definitely my best purchase so far!

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  • Silvana

    (2 out of 5)

    I was disappointed that this product did not really significantly improve any of my fine lines. I also didn't notice any improvement in skin tone or brightness. I really wished for a result I could justify re-purchasing, but it was not the case for me.

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  • Amelia

    (5 out of 5)

    I started using E'shee Clinical Esthetic Elixir Kl Therapy about 3 months ago constantly.. I use it at bedtime and sometimes during the day providing I'm at home and can pile on all of the incredible nutrients (50% of the time) . I must say though, my skin looks absolutely beautiful & Marta and I are close in age. I have been using the AQ Eye Serum with the Sciote Vitamin C eye Treatment during the day (recommend by Marta! Thank You so much Marta) & the Eshee AQ Gene Therapy eye cream at night. I then top off with a light layer of the Eshee Cream and Villa! I bake for the night and hope for the best!!

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  • Debora

    (4 out of 5)

    I really love this product, hate the packaging and price. It helps reduce redness and improve my skin's overall tone and elasticity. No matter how careful I am in dispensing the product - and I have read through the tips given here - I always have considerably more than one or two drops stuck in the cap rim. Results are the most important thing, so I continue to use it despite the price and the waste.

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  • Marta

    Hi Ha, there is a video on how to open/use the product. Go to the video tab and scroll down - it is the last of the four videos

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  • Ha


    Anyway to record a video on how to actually get the product out of this bottle? Would be great to view before purchasing since this is the main issue from these reviews.


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  • Janice

    (4 out of 5)

    I love the feel of my skin after I use this. My face feels velvety and firm, and it is definitely more even in tone after using most of the bottle. I would give this a 5, but it is kind of a pain to pry off that little cap and not spill any.

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  • KathyR

    (5 out of 5)

    I use the Life Ki Therapy and love it. My skin looks healthy and at 51 have but the lightest lines. I am often mistaken for 10 years younger. I like putting this oil serum on right after washing my face, while it is still moist. Three drops do my face and start down my neck. I had a problem waiting for it to roll out of the bottle until I read Martha's shake it down to the applicator tip method. I will not give this stuff up!

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  • Marta

    Hi Kimberly, I am thrilled that you got on so well with this. I keep coming back to it. I just opened what must be my 5th bottle. Like you, I find that a little goes a long way and that I can keep a bottle going for 3 months at least. Regarding the packaging, there is a technique that the nice people at E'shee shared with me. Tip the bottle right over so the nozzle is facing the ground. You should be holding the glass bottle. Give it a firm downwards shake - a couple may be necessary - so that the serum fills the plastic nozzle completely. It must be full. Then squeeze the nozzle GENTLY to release a small (lentil sized) amount of the serum. On no account squeeze too hard. I follow these instructions and it works for me every time.

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  • Kimberly

    (5 out of 5)

    I just wrote a review, and wanted to add an addendum. Regarding the packaging, I had the same issues as most people using this, and hated the packaging. So, I developed my own style of application. Now I know that keeping the ingredients in their special packaging for freshness and efficacy are important. However, after the usual troubles with the rubber top, I decided to take the top off very quickly and clean out the excess by using the appropriate amount on my face. After I got the rubber spout cleaned of product, I would quickly take off the rubber top, tip the bottle on a very clean fingertip or two, quickly put the rubber top back on the product, and apply to my face and neck. I don't know if this is a "no/no", but it worked well for me and I did not lose product nor did it seem to effect the product negatively. Thanks!

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  • Kimberly

    (5 out of 5)

    "Almost perfect" would be the title of my review for this product. I took this little jewel on a trip up north with me recently. It was my first time using it, and I honestly didn't expect much out of it. WRONG! This gem of a skincare serum puts E'shee at the top of my list once again. Not only did my skin begin to glow as early as 2 weeks into using it, but I honestly do think that after over a month's use, it has evened my skin tone a good bit, makes my skin have that "glowing look", and I am even pretty sure it helped some with the lack of firmness in my 50+ neck. Now that is a big deal for me as my neck is my biggest skincare concern.

    Since my other products were on back order, this product and my regular moisturizer were all I had to fend off the elements of a Colorado winter (not my regular cliimate). Although I used more of it than I would have if I had my other products, I would say it will last between 2-3 months, depending on if you use it in "spots" or all over your face, and how often you use it. I used it twice a day as it was all I had. I am serious when I say it only takes a few drops. Also during this time, my friend who was with me used this product. She is in her early 60's, and one day while sitting at the computer table, I looked up at her, asking, "when did you have time to put your makeup on"? She answered that she hadn't. Her face was glowing and was much more even toned. She had been complaining of some "brown spots and uneven tone". Knowing what she was using on her face prior to this, I am almost positive it was the E'shee that made the noticeable difference in her face in 2 short weeks. While it may not work as well for everyone, this reviewer certainly wants to put E'shee 7 in her daily routine, if she can afford it!

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  • Sara

    (5 out of 5)

    I alternate between this serum and the E'Shee Cellular Repair, and have been using both for a bit over a year now. I can honestly say that my skin has never looked better: it is healthy, glowing, and even in tone. I never wear makeup anymore except for a touch of eyeliner and lipgloss.

    If I run out of KI, I find that the Cellular Repair works well to keep redness down and my skin tone even -- but KI adds tautness and glow. I have tried several other E'Shee serums, but these are the two I consider truly essential and worth the money.

    I have never had any problems with the E'Shee serum packaging. When I'm traveling, though, I do use a strip of masking tape over the top to make sure the little tip stays securely in place!

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  • Jennifer

    (2 out of 5)

    I wish I could give this a 5. I really wanted to, because I am a such a super fan of far infrared as an ingredient. I have tried e'shee products a couple of times to give them a chance and I just cannot get past the bottle issues. I find that rubber top that I am supposed to put on fidgety and impractical. The product gets stuck in there and it gets a bit gummy. I am not shy about spending money on products that truly deliver, but there must be a better solution to the delivery on this, as I agree with others who mention that for the price, why have any of it wasted? I may give this line yet another chance, because I am a fan of their ingredients and I know that Marta's choices seem right on.....but I'm just not sure about it yet.....

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  • jennyR

    (4 out of 5)

    Caveat: "good, thus far."
    I've only used this for a week or so twice daily, but a client complimented on my skin today!! Not sure if it's because I'm treating my skin much more gently since I started with TIA, or if it's for Elixir of Life Serum. My goal is to be like Marta, and be able to go without makeup.

    Marta, I know you're on your 4th bottle, and now use it every 3 days. When did you stop using it twice daily or daily?

    Also, should I use just one serum over my face daily, or layer one over another? Afterwards, I use either moisturizer or my now BELOVED Prana sunscreen.

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  • Jessica

    (2 out of 5)


    I've reached the end of the bottle. What I did like - it seemed to moisturize without feeling greasy, very light and refreshing. It seemed to help slightly with redness, though I noticed no difference on capillaries or fine lines/wrinkles. This did nothing for eye texture or circles, either. Overall skin texture seemed slightly improved, though this could be attributed to use of LED/ultrasonic devices too.

    What I didn't like - overwhelmingly, the packaging. I just can't understand how such an expensive and cutting-edge product can have such sub-par packaging. After taking the suggestion regarding the package wasting product, I still had problems - slightly less, but once a week I'd notice a bit of product under the cap, which then dried to a more sticky and gooey texture I tried in vain to use on my hands or decollete.

    Overall, between the minimal skin benefits I experienced - I'm a 33 year old woman with some sun damage in the form of fine lines and hyperpigmentation, with broken capillaries around the nose and a bit of redness - and the package wasting a significant amount of product, I can't recommend this. I'll be wary of spending $150+ on a serum in the future.

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  • ade

    (5 out of 5)

    This product is youth in a bottle! I look immediately refreshed after applying it. I think I might be hooked for life :o

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  • Marta

    (5 out of 5)

    Hi Rollinpics, I am sorry to hear this. I am not sure what you mean by spillage, but did you see Preksha's comment below yours. There is a technique to tipping the bottle over and patiently waiting until the product has accumulated in the spout and then squeezing it very gently - and I mean very gently. This has resolved any problems in my experience. Nonetheless, I hear you and will pass on your comment to E'shee

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  • rollinpics

    (3 out of 5)

    I'm on my 2nd bottle of KI and though I do like it a lot especially after Martha's review -- I have to say the Packaging issue is a a MAJOR issue at close to $200.00 a bottle kind of disrespectful to customers.... why should I, after spending so much, even have to worry about it spilling and not getting complete use of all product??
    I've been trying all sort of angles etc and the issue is still there...
    I will seriously reconsider ordering this again due to packaging...
    NOT COOL is right!
    I definitely lost quite a bit of product ....

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  • Preksha @ TIA

    Hi Jessica,
    Thank you for your feedback regarding the E'shee KI Serum. We're sorry to hear you're experiencing issues with the E'shee bottle. We have spoken to E'shee regarding this issue and they have given us the following suggestion:

    You're absolutely right, one-two drops of the product can accumulate underneath the cap. It happens when a customer opens a bottle and applies applicator when neck of the bottle is still a little wet; or then someone squeezes an applicator too hard. I recommend to make sure the neck of the bottle is completely dry before applying an applicator. And not to apply too much pressure on it."

    Marta has also experienced this issue, and taking into consideration E'shee's suggestion, no longer has the leaking issue. If you have any other issues, please feel free to contact us at and we would be more than happy to help.


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  • Jessica

    (3 out of 5)

    I'm only half way through my bottle, so will update when I actually finish. Upon Marta's advice, I discontinued glycolic treatments to focus solely on this. I missed the baby soft feeling and smooth appearance I got from PTR Un-wrinkle Peel Pads, but this is supposed to work without exfoliation. As of now I see nothing, save a little redness I attributed to the peel pads. I've been testing it on forehead lines, "bunny" lines at the top of the nose/inner eyes, nasolabial folds, and around the lips morning and night. One thing I HATE is the packaging. The weird plastic dropper/ dispenser that sits on top of the product isn't airtight and no matter how I adjust it, it leaks out around the edges - not cool at nearly $200 a pop! I actually had to leave it home on a 6 week tour because I was afraid the airplane's pressure would cause even more loss. It's not a bad product, I only use a few drops and my skin - combo skin that gets oily with surface dryness - isn't asking for anything else, which is awesome. I will wait until the bottle is finished for the final verdict, but so far there are better ways to spend your $189.

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  • Holly

    (5 out of 5)

    This product is incredible - I bought it in the hope that it would help reduce the dark circles under my eyes. Two weeks in and I still have panda eyes but oh my goodness, my skin is looking at least 5 years younger! Particularly the skin under one of my eyes - which has really depressed me this year - it was looking pale and thin compared to the rest of my face. And one eyelid was becoming noticeably crepey. Creepy! But now even my skeptical husband has noticed the difference - and I've been so busy lately that my skin care routine has been limited to about two minutes am and pm. I've even run out of day cream so have only been moisturising at night. And I haven't used my LED device for over two months. So I can't believe how much difference there has been in the texture of my skin since using this product - it is literally holding up the fort on its own. I've already bought my second bottle - because I'm terrified of running out and having to wait for it to be shipped to me in Australia. I seriously recommend this product and can't thank you enough Marta for recommending it. Ciao xxx

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  • Pam

    (5 out of 5)

    Happy to see you like this too Marta. I have used this and love love it. I will go full circle trying other stuff but have to say I still love using this best. It felt so good on my skin and seemed to work almost miracles.

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  • Marta

    April 11, 2014


    Hi Jo
    I was once told by another manufacturer using a growth factor that was also at the end of the ingredients list that it was in proportion to the amount of growth factors in the body. I don't know whether that was BS or true. But I do know that they are potent (and expensive). Also - sorry, I'm a broken record on this one - the good quality ingredients don't have to be in huge concentrations to work. For example, I'm always very skeptical of brands touting, for example, 20% Matrixyl. All the clinical trials are with 4% only and there is no need for 20%. I think, in the end, you have to trust the brand and the way it formulates.

  • Jo

    April 11, 2014


    Hi Marta. I noticed the growth factor ingredient is the very last one on ingredients list, implying its a very small amount. What's the deal with that? Is there enough of this growth factor to be effective!

  • Marta

    September 12, 2013

    (5 out of 5)

    Shalini, BRAD Multi-peptide and E'shee KI are two of my staples. I typically use KI in the morning and BRAD in the evenings. This works out very well for me.

  • Shalini

    September 12, 2013


    Hi.I recently ordered the brad multi peptide from the Tia shop, owing to the glowing reviews:)
    Now I am tempted to purchase and add the KI to my arsenal. I am wondering however if its safe to combine the brad and KI into my regime or would the two negate the effects of each other in any way. I'm 35 looking to prevent / delay signs of ageing.
    Would appreciate your suggestions/ advise!
    Thank you

  • Pinky

    March 21, 2013


    Does it come in a sample size? Sometimes I break out from products that contain calendula and chamomille, which is a shame since they're in so many natural products. Other times, as with Reluma's cleanser (which has calendula), I do just fine.

    If there is no sample size does the company have a return policy?

  • Marta

    January 31, 2013


    Hi Marie, I use this serum during the day (not at night) and I don't need to layer a moisturizer over it. I have normal to oily skin. I think (combined with regular use of ultrasonic and LED, that it is helping lip lines very much.

  • Marie Lavinio

    January 30, 2013

    Marie Lavinio

    Do you need to layer the serum with a moisturizer at night? During the day I assume you wear sunscreen over the serum? How is it doing on lip lines? Thank you!

  • Marta

    October 11, 2012


    Hi Maria, this is lighweight gel. It does not dry my skin out at all. FAR isn't really a clay, more of a mineral. In any case, I don't need to wear moisturizer with it at all. Nor has it made my (rather ruddy) complexion any paler. I bought it - full price, no discounts - with my own money and so, yes, I do think it is worth it. My first bottle (which still has a few days to go) has lasted more than two months and I haven't been especially careful with it. Judicious users could keep it going for 3 months I would think.

  • maria

    October 11, 2012


    Does this dry out skin? ...I'm thinking wtih a clay-like substance that could happen. Also - with a serum i also don't want it oily, as i like it to compensate for the oily tendency of sunscreen and foundation. Another question: does it make your skin too pale? I've been finding with Led Green and with IPL my face has become paler -- thanks! In addition: what a pricetag! Is it worth it?? I've used Lancome Visionnaire for 2 days and like it though I also am very much an ingredient reader and wasn't too impressed...but for now i'm giving it a try - thanks

  • Marta

    October 10, 2012


    Pam - I am so happy to hear this. My results are so amazing that I have been pinching myself. It is very, very reassuring to have it confirmed. Many thanks for sharing.

  • Pam

    October 10, 2012


    Happy to see you like this too Marta. I have used this and love love it. I will go full circle trying other stuff but have to say I still love using this best. It felt so good on my skin and seemed to work almost miracles.

  • Marta

    September 13, 2012


    Hi NJ, I feel that they are complimentary. In fact, I am currently using Kl with Control at night or on days when my skin is drier, with Control layered over.

  • NJ

    September 12, 2012


    Hi Marta,

    Exciting review! How do these results compare to YBF Control, which I know you love? I haven't had a chance to use Control yet. Thanks for all you review and do!


  • Water (Aqua)
  • Butylene Glycol
  • Hamamelis Virginiana (Witch Hazel) Extract
  • Dipropylene Glycol
  • Glycerin
  • Epilobium Angustifolium Flower/Leaf/Stem Extract
  • Ethoxydiglycol
  • Chamomilla Recutita (Matricaria) Extract
  • Calendula Officinalis Flower Extract
  • Panax Ginseng Root Extract
  • Phenyl Trimethicone
  • Glyceryl Diisostearate
  • Sodium Stearoyl Glutamate
  • Hexylene Glycol
  • Fructose
  • Biosaccharide Gum-1
  • Glycereth-25 PCA Isostearate
  • Polysorbate 20
  • PEG-40 Hydrogenated Castor Oil
  • Alanine
  • Glutamic Acid
  • Allantoin
  • Panthenol
  • Dipotassium Glycyrrhizate
  • Carbomer
  • Xanthan Gum
  • Hyaluronic Acid
  • Far Infrared Ceramic Powder
  • Fragrance (Parfum)
  • Arginine
  • Disodium EDTA
  • Phenoxyethanol
  • Methylparaben
  • Propylparaben
  • Methylisothiazolinone
  • CI 19140
  • CI 16035
  • aFGF (Recombinant Human acidic Fibroblast Growth Factor)

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Tip the bottle over and wait until the product has accumulated in the spout. Squeeze gently to release product. Apply 2 to 4 drops on the face, neck and decollete, including eye area (can be applied to lower and upper lid). Use 1-2 times daily. Suitable for all skin types.

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