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iS Clinical Active Serum Review

is a Solution for:
Acne, Hyperpigmentation, Wrinkles
is clinical active serum
September 3, 2015 Reviewed by TIA Community Member 5 Comments
TRU Rating
While it may work for some, beware of adverse reactions


Contains several natural ingredients


Caused skin irritation, redness and small bumps

by Karen Prince

When asked if I would test and review a product, iS Clinical Active Serum ($130), that Marta is testing, I eagerly awaited for the product to arrive. I have been fortunate to have reviewed several products that Truth in Aging offers and each one has been a “home run, out of the park” experience. The fact that my 29 year old daughter told me that she had been using this exact product with much success after four months really generated more excitement for iS Clinical Active Serum.

Well into my fifth decade, I have dry to normal skin, drier in the winter months, but definitely with the humidity in the spring and summer, I need to change up my skin care regimen and routine.

I expected this product to reduce the appearance of fine lines and wrinkles, minimize my pores, diminish the appearance of hyperpigmentation, and as stated on their website, to provide rapid and long term results, leaving my skin prepped for the next steps of my routine: SPF and moisturizer, having already cleansed and toned my skin.

The ingredients, found on the product’s website sound terrific,this product seems ready to deliver: Water/Aqua/Eau, Glycerin, Glyceryl Polyacrylate, Butylene Glycol, Alcohol Denat., Saccharum Ofcinarum (Sugarcane) Extract (Extrait de Canne à Sucre), Vaccinium Myrtillus (Bilberry) Fruit/Leaf Extract, Triethanolamine, Salix Alba (White Willow) Bark Extract, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol.

Sugar cane is a source of glycolic acid, great for gently exfoliating for renewed complexion. Bilberry extract is a source of lactic acid, which is a natural exfoliant with moisturizing properties. White willow bark is a source of salicylic acid, for deep cleaning the pores, while Arbutin and and mushroom extract are used to diminish hyperpigmentation.

Quite honestly, my expectations were met with disapproval. I do not have sensitive skin and am easily able to change up my skin care routine when I want to try new or different product that Truth in Aging has discovered, tested, and favorably reviewed. I REALLY wanted this product to work. I even called my daughter to see if she had any initial irritation, redness, or flaky patches. She indicated that she did, but continued using the product and was ultimately satisfied with it. I wanted to give this product a good trial period and an honest review, so I continued to use it.

The sensation, upon putting the serum on my face daily was cool, but irritating and harsh. I believe this is as a result of the amount of alcohol and menthol used in the ingredients. I then changed my routine to using iS Clinical Active Serum every other day, seeing if my skin inflammation would be reduced. After several weeks, the redness remained and small bumps began to appear and my skin became over dry.

I am able to use retinoids, which are stronger, with no problem. They typically contain ingredients chemically related to vitamin A for the treatment of acne, but more popularly designed for wrinkles and anti-aging.

 I am a long time Truth in Aging community member, so when asked to try a new product and write a review I am happy to contribute, as the information found on the TIA website has significantly contributed toward my skin, neck and décolleté looking years younger as a result of consistent use of a variety of products. Every other product that I’ve reviewed has been a WINNER…and I had high hopes for iS Clinical Active Serum. I could not write a review that was not truthful about my experience. I looked at many reviews of this particular product in several places and some were very favorable. Perhaps this was not a good match for me.

Does it do what it says it will do? No, my skin couldn’t tolerate it. I would not recommend this product from my six week experience.

  • January 1, 2018

    by ava

    such a bummer that this didn't work for you! This is my favorite, i think it works so well!

  • November 16, 2017

    by Lois

    I just had a facial 5 days ago and they used this product. As first I thought the stinging, redness and bumps was just because of the microdermabrasion treatment I had but it continued and got worse. I spent $600 on these products because initially I felt amazing. I stopped using it but it is taking forever for my skin to get back to normal.

  • August 30, 2017

    by Kristina

    I am just writing my honest account of my first experience of this product. I have to say it came very highly recommended by my friends who use it, love it's results and have not suffered at all with irritation.

    However.. 4 days into my day and evening gentle use.. and day 5 I have woken up horrified that my face (forehead, nose and area around nose has small red bumps and has clearly not taken well to this new product. My skin feels rough, bumpy and I am really not very happy. I have no itching or burning but I refuse to continue using it. I have written to my authorised seller to ask for a refund.

    I have to say, I have had glycolic peels in the past and don't suffer from sensitive skin but this product just is not right for me.

  • September 23, 2016

    by Li

    I wouldn't recommend this product to anyone. It literally destroyed my skin! It is as described above harsh and irritating, probably due to the massive amount of alcohol in it. With only four days of use I've experienced really dry skin, redness and small bumps same as the reviewer, so I stopped using the product immediately. Two weeks have now passed, and the bumps and redness are slowly fading away.

  • September 8, 2015

    by Kim

    Thank you for your honest review and thx to TIA for publishing. This is an example of where a site's integrity and commitment to providing truthful reviews based on real usage experiences is beyond appreciated. The value of non favorable reviews that gives reasons as to why the product didn't work is just as valuable as favorable reviews. The fact you noted the inclusion of menthol and alcohol as to likely being irritants for you helped me know this product wouldn't work for me either as I cannot tolerate even small amts of alcohol and no amount of methol on my skin. Truly am grateful for the continued publication of such important user experiences as yours. Best regards! And looking forward to future reviews on other products you do for TIA.

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