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E'shee Clinical Esthetic Cellular Repair Serum

E'shee Clinical Esthetic Cellular Repair Serum

Size: 0.34 fl oz (10 ml)

E'shee Cellular Repair Serum is a revolutionary, multitasking anti-ager clinically designed for anyone looking to boost collagen production, increase skin's firmness, smooth fine lines and wrinkles, all while repairing scars, improving texture and reducing redness. This concentrated serum uses innovative, advanced and powerful ingredients, like the FGF1 gene, to completely renew, repair and enhance your complexion, leaving your skin looking firmer, clearer and more youthful than it ever has before. Just like all of Truth In Aging’s products, our community members have tested and reviewed E'shee Cellular Repair Serum, so that you can be completely confident that this item will re-texturize, firm and revitalize your skin.

E 'shee Cellular Repair Serum is designed with 99 % pure bioengineered FGF1 gene—a human acidic fibroblast growth factor. This ingredient triggers cells within your body to produce new, undamaged cells, increasing the thickness, stength, plumpness and elasticity of your skin. Hyaluronic acid allows the skin to retain moisture, leaving your complexion looking supple and restored. Like all products in the Truth In Aging store, it has been tested by members of the community so that you can trust it works.

Tested for at least 30 days by Marta:
E'shee Clinical Esthetic Cellular Repair Serum is one of the most powerful serums that I have ever come across. I use it to target those really tough wrinkles so that a little goes a long way and I get more bang for my buck. The results are impressive. Used carefully, the bottle will last a good three months or four months.

This serum is hugely beneficial for rosacea, broken veins and deep wrinkles. The key active is the cutting edge FGF 1 (a Recombinant Human acidic Fibroblast Growth Factor). Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis and wound healing. FGF1 is rather bossy and tells other FGFs what to so. It signals FGF2 to get on with fibroblast growth and collagen production, hyaluronic acid and elastin, while getting FGF7 to get busy with hair follicles and grow hair. FGF7 is also responsible for keratinocyte resulting in rejuvenated skin.

They also support angiogenesis, which is the growth of new blood vessels. Certainly, broken veins seem to diminish with this serum.

The horse chestnut is a well-known repair for broken capillaries. Horse chestnut trees (particularly the seeds) contain a saponin called escin. This is supposed to strengthen veins and capillaries by blocking an enzyme called hyaluronidase, which can breakdown of proteoglycans (part of the structure of capillary walls).

The only other botanical is mulberry. This is typically used in skincare as a whitener. Studies have been shown mulberry leaf extract to inhibit tyrosinase activity. Additionally, several phenolic flavonoids, such as gallic acid and quercetin, and fatty acids, such as linoleic acid and palmitic acid, have been isolated from its leaves. With sodium lactate and lactic acid providing exfoliation and sodium hyaluronate, this formulation covers most bases.

We cannot ship E'shee products to Taiwan or Korea.
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$ 179.00
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Our Take

When I first saw E'shee Clinical's collection of serums (I was sent free samples), I didn't know what to make of them. The prices seemed to be in inverse proportion to the size with the E'shee Clinical Esthetic Cellular Repair Serum ($179 in the shop) for a Liliputian 10 ml or 0.34 fl oz. As I said,... read more

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6 member(s) found this review helpful


12 Reviews
  • Tena

    (3 out of 5)

    The only down side for me is that it didn't seem to last me as long as some others I have used. Also, some reviews are mentioning that it was sufficient for three months.. Well, my vial has lasted about a month and I was using very carefully. I didn't even use it on my neck, even I had issues (broken capillaries).. I have to admit that this is really heavy hitter. This serum helped me to preserve my skin through very stressful and painful period in my life. It did also some improvement on my skin around the eyes. I used it with alpha&omega cream. Maybe I'll purchase it again.

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  • Ros

    Is this safe to use in tear trough area? I'm only 23 and very porne to breakouts, so I can only use noncomedogenic products; does this fall under that category?

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  • Terri

    I bought a bottle of this and it did seem to help with redness, but not the broken cappilaries. Im curios how many people who have tried this product, have actually been diagnosed with Rosacia? My problem is not Rosacia, although I do have the broken blood vessels along with a mask of redness.
    The thing is, being the this I stated above, is this be best serum for me or could you suggest something that may work better? I never have breakouts or the little bumps as have been described. But I would sure like to know if there was any product I may have missed that may take care of these two issues? I'm pretty sure I've tried everything I could find, but to no avail. Any suggestions would be greatly appreciated.
    Thanks so much,

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  • April

    (5 out of 5)

    I have used this product off and on for the past two years. My rosacea when severe, this is the one product that will always calm it down. Daily, I use some sort of sulfur gel (even over the counter from target works well) but hands down this is the best product I have found and much cheaper than a vbeam laser treatment that only lasts a month or so. I also use reluma and have found that when I use it consistently my flare ups are less frequent. I purchased both products from this site. I have read all sorts of things on what causes R and no one seems to know for sure. My derm feels there is some validity regarding dermal mites so now I change my pillow case regularly.

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  • Sara

    (5 out of 5)

    I have mild rosacea; it manifests as itchy red bumps and occasional small reddened blood vessels on my cheeks and forehead.

    I have been using this product for about 9 months now, and I absolutely cannot be without it. It dramatically reduces redness and inflammation. While my broken blood vessels are not completely gone, they are very much minimized. My skin is healthy and glowing. Rosacea flareups are now much, much smaller and rarer than they used to be, and they don't last long.

    This is the most expensive product I have ever used, but it's worth every cent. I don't know how people manage to make it last for over 3 months, though! I go through a vial a month, using it once or twice a day.

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  • Dawn

    (1 out of 5)

    Do your broken veins get worse before they get better? I have been applying product 2x's a day for two days now and I swear they are worse! Trying to decide if I should keep using or if I just threw away $180.00. Also, a little disappointed that they are offering a 20% discount on E'shee products less then a week have I purchased for full price.

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  • Dawn

    (1 out of 5)

    I just bought this product and I want to know if the broken veins get worse before they get better? I have applied product 2x's a day for two days now on my broken veins around my nose and under my eyes and I swear they are worse! Trying to decide if I should keep using or if I just threw away $180.00. Also, a little disappointed that there is a 20% discount offered on E'shee products less than a week after I bought for full price.

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  • Jan C.

    (5 out of 5)

    This stuff is Magic! I've only been using it for 2 weeks & ALL the nasty red veins on my nose & cheeks are getting lighter. I had some brutal veins on my nose where my glasses sit & they're a lot less noticeable. Woo hoo!

    Totally worth the price. Luckily, a little goes a long way!

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  • Marta

    (5 out of 5)

    Hi Thea
    I have read some relatively new research about the cause rosacea. in 2007, Dr Richard Gallo of the University of California discovered that peptides known as cathelicidins and the proteolytic enzymes that activate cathelicidins in the skin are abnormal in patients with rosacea. This revelation turned out to be a breakthrough and sent scientists off in a new direction.

    In my experience, rosacea triggers are very immediate and I would think that given that you have been using the E'shee for several weeks, you would likely have had a reaction by now. I have used this product on and off for a couple of years and haven't experienced a flare up.

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  • thea

    (3 out of 5)

    I really can't fairly review this product as ive only been using it for weeks but some research that ive done has me concerned. Fgf 1 is a supporter of angiogenisis but wouldnt' that make rosacea worse? According to some of the information i have found fgf is a supporter of VEGF and VEGF is in overabundance in the skin of those with rosacea. A medication called dobesilate (also used to surpress tumor growth) has been used succesfully to treat rosacea as this medication surpresseds fgf and angiogenis. According to some of the research, rosacea is a disease of uncontrolled angiogenisis and dialated (not "broken") blood vessels. Wish i would have done this research prior to spending170 big ones on a serum that i am now to scared to use. Im hoping someone has more info regarding angiogenisis/rosacea/fgf...REally wanted this to work but now i don't think ill ever know out of fear of making things worse.

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  • Jeri

    (5 out of 5)

    I have just ordered my third vial of E'shee's cellular repair serum. Each vial has lasted about 3 1/2 months, which is what E'shee and Marta both agree is a fair amount of time. I LOVE THIS SERUM. It really has diminished the broken capillaries in my cheeks, and calmed my rosacea. Those Charlie Brown wrinkles are smoother, too. I wish that my skin was simply is downright paranoid, defensive, resentful and vengeful. It took three weeks to recover from three days of Chella's Master Protocol, and two weeks to get over three days of ReLuma. This product is so special to me because it has improved the texture and tone of my complexion, and is correcting some of my concerns. Thank you, Marta, for the introduction.

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  • Junko

    (4 out of 5)

    After using E’shee’s Repair Serum for 6 months on the bridge of my nose and around my eyes, I’m not proclaiming it a miracle serum, but it DID significantly reduce and repair the depth of the wrinkles on my nose and crows feet. For this, I will forever be grateful to E’shee’s Cellular Repair Serum.

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  • Marta

    September 19, 2016


    1,3 butylene glycol is generally considered to be safe:

    There are concerns (toxicity and irritation) with propylene glycol:

  • **

    September 19, 2016


    Dangerous as it contains butylene and propylene Glycol. Harmful ingredients

  • Shalini

    April 6, 2014


    Hi. I recently purchased the Eshee KI Elixir and quite liked the results. I have also read wonderul reviews about the E'shee Serum Cellular Repair. I need to understand however, what is difference between the two products in terms of ingredients and skin concerns/treatment?
    Your advise would be greatly appreciated :)
    Thank you

  • Marta

    March 14, 2013


    Hi Jurgita, I don't think you need this kind of serum as it is really for wrinkles and firming. These are not issues that you mention. Good moisturizers (with helpful antioxidants)for combination skin that you might like to look at are La Vie Celeste Day/Night Cream, Your Best Face CE, and Snowberry Bright Defense[]=27

    I have just put up a post for suggestions for enlarged pores:

  • Jurgita

    March 14, 2013


    I'm just wondering is this serum suitable for my skin, as I'm 34 y. o., my skin is mixed type, with very dry and sensitive cheeks and quite oily, large pores nose/forehead area..

  • Janet

    February 8, 2013


    Marta: Thanks to you, I LOVE the KI, my skin is much firmer, and noticeably better. The KI though, has not touched my redness. Are you recommending use both the Cellular repair and the KI?
    thank you

  • Howard

    September 28, 2011


    So agreed ..Best Bang is my motto and feeling. Please educate me on e'shee and how it could compliment my 50 yr old male skin

  • marta

    March 27, 2011


    Hi Jennifer, I believe that the horse chesnut is good for broken capillaries. I don't know if E'shee would be good for dark under eye circles. Somehow I doubt it. How about trying SenZen's Double Dose

  • Jennifer

    March 26, 2011


    Hi, Marta--thank you for your diligence and integrity in the midst of so much mis-information with anti-aging products. I was wondering if you thought this would be a worthy product against dark circles caused by thin skin/visible blood vessels and pooling because of the chestnut ingredient... thought I read somewhere that this an effective ingredient for that. Seems I am still on the hunt for a worthy product (Correct, although effective, caused an allergic reaction for me). Thank you!

  • We are voted “Best anti-wrinkle product 2010″! | E'shee means Personal

    January 10, 2011

    We are voted “Best anti-wrinkle product 2010″! | E'shee means Personal

    [...] being said, E’Shee’s Serum Cellular Repair was the best anti-wrinkle product I found in 2010. The standout active is a recombinant human [...]

  • marta

    January 6, 2011


    Kimberly, take a look at our post on propylene glycol. I'd rather avoid it, but I am not sure that you need to be scared of it:

  • Kimberly

    January 6, 2011


    I agree with Susan, propylene glycol scares me and the minute amount of HGF does not correspond for its price. I need to know of any other products with HGF listed higher on ingredients list, please ty

  • FGF1 and human growth factors- what is it | E'shee means Personal

    June 25, 2010

    FGF1 and human growth factors- what is it | E'shee means Personal

    [...] are two notable things about E’shee’s serum, which I reviewed and recommended a few weeks ago and which I am still using in my daily regimen. [...]

  • Susan

    May 29, 2010


    It seems a shame that the HGF ingredient is last on the list. With such a small amount used and no other extraordinary ingredients, the price hardly seems justified. I'm especially unimpressed with propylene glycol being #3 on the list (behind water and witch hazel). I'll save my money for something more impressive.

  • marta

    May 27, 2010



    The E'Shee does not have a fragrance and it is a colorless gel in a small clear bottle - very unisex, totally discrete. I would definitely recommend investing in really good serums rather than Botox. The cumulative effect of these ingredients is only good, whereas with Botox people tend to need it more and more frequently.

  • Richard

    May 26, 2010


    Hi Marta!

    Would you recommend this serum for men? Is it has heavy perfume smell to it? I’m 48 and I need some “heavy artillery” around my eyes and on the forehead. . I’m in sales, so I have to look good to be able to keep up with younger competition. I’ve been using Botox for past 4 years. Its o’k, but works on me only for about 3 month, it’s painful and expensive. This one not cheap, but if it’ll last me for same 3 month, it looks like better alternative. It will come to something like 2 dollars per day… I think I can afford it. Please advice.

  • marta

    May 26, 2010


    Great suggestions Lori and Junko. Watch this space.

  • Junko

    May 25, 2010


    The best 5 catagories seem to have a nice range of pricing. Eshee is the highest priced of anything that's been reviewed yet I believe (someone correct me if I'm wrong). A Best Bang for Your Buck catagory might be nice to pull in the best values from all catagories?

  • Lori

    May 25, 2010


    Perhaps this has already been done but I'd love to see a round-up of best "value" products in the various categories. So often the reviews are wonderful for items many of us simply can not afford. We need a list of "heavy hitters", like Folligen, that don't hit your wallet hard!

  • Junko

    May 25, 2010


    Please post back Marta with final thoughts when you've emptied your Ampoule.

  • marta

    May 25, 2010


    Long term the growth factor should be eliminating/repairing them. That's the the theory but I'd need to keep using it. I have to say that so far the - possibly superficial - effects are very good though.

  • Junko

    May 25, 2010


    Marta, can you say yet whether you think the repair serum is eliminating wrinkles or just temporarily plumping the skin and smoothing them?

  • Kathy

    May 24, 2010


    Did they give you any samples to share with deserving followers of TIA? hint, hint, hint?

  • Aqua
  • Hamamelis Virginiana (Witch Hazel) Distillate
  • Propylene Glycol
  • 1.3 Butylene Glycol
  • Aesculus Hippocastanum (Horse Chestnut) Seed Extract
  • Glycerin
  • Morus Alba (Mulberry) Extract
  • Tinocare GL
  • PEG-40 Hydrogenated Castor Oil
  • Sodium Lactate
  • Sodium Hyaluronate
  • Triethanolamine
  • D-Panthenol
  • Lactic acid
  • Carbomer
  • Allantoin
  • Phenoxyethanol
  • FGF 1 (Recombinant Human Acidic Fibroblast Growth Factor)

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Duration: 1:35

After cleansing and toning your skin, apply 2 to 4 drops on the face, neck and decollete, including eye area (can be applied to lower and upper lid). Use 1-2 times daily. Suitable for all skin types, especially rosacea prone skin and those with broken capillaries.

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