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Dr. Dennis Gross Triple C Peptide Firming Oil Review

is a Solution for:
Dull Skin, Fine Lines, Lip Lines, Sagging Skin
dr. dennis gross triple c peptide firming oil
August 31, 2015 Reviewed by Marta 8 Comments
TRU Rating
This rapidly absorbing oil lives up to its claims


Minimizes lip lines, firms skin


Contains phenoxyethanol, feels oily

When I told Dr Gross that I was most concerned about my lip lines, he was insistent that I incorporate his Triple C Peptide Firming Oil ($62 in the shop) into my regimen (along with the Alpha Beta Peel and Moisture Cushion). One month in, I am seeing a very subtle decline in my stubborn lip lines and overall my face is more radiant and — surprisingly firmer. Triple C Peptide Firming Oil lives up to its name in every respect.

Triple C

There are three forms of vitamin C: ascorbyl glucoside, ascorbyl palmitate, and tetrahexyldecyl ascorbate. The first, ascorbyl glucoside is a stable derivative of vitamin C that research has shown to have antioxidant and skin lightening effects (more so than plain ascorbic acid). Ascorbyl palmitate is also known as vitamin C ester and has been shown to boost collagen production (the only vitamin that can do this) and works synergistically with vitamin E (also in this serum). The third is tetrahexyldecyl ascorbate, which is very stable and powerful at low concentrations.


Since all good things seem to come in threes in this serum, there are three peptides: tetrapeptide-21, palmitoyl tripeptide-1 and palmitoyl tripeptide-28. The first of these goes by the name of TEGO Pep 4-17 and increases collagen synthesis, penetrating the skin well due to its small molecular size. Tripeptide-1 is said to stimulate the synthesis of collagen I and III, fibronectin and laminin. The third peptide is supposed to bind to a growth factor and mimic the natural regeneration of the extracellular matrix.


With collagen-boosting vitamin C and potent peptides, this serum should boast “firming” in its moniker. And deservedly so. After a month of use, I have really noticed the difference — especially around the jawline and the cheeks.


This is where my first (actually only) caveat comes in. If you don’t like oily products, you might not like Tripe C Peptide Firming Oil. Initially, it feels very oily. The important thing to remember is that a very little of this serum should be applied. As a rule, I’m not wild about oils and I was worried that I wouldn’t like this one. But I quickly got over that when I realized how rapidly and evenly it absorbs.

The serum’s base is squalane. A properly refined squalane can permeate into the skin at a rate of 2 mm/second — hence the rapid absorption effect I noted when applying this serum. Squalane is in human sebaceous secretions and declines dramatically as we get older. The many antioxidant oils include rose, rosemary, evening primrose, argan, avocado and more.

Dr. Gross could have inserted vitamins into his serum’s title as well. In addition to all those Cs, there are vitamins K, A, D and E. I especially like the vitamin K, which you don’t come across all that often as it is supposed to help with spider veins, and vitamin D, in which almost of all of us are deficient. But wait! There’s vitamin H and F as well. I don’t think I knew that the vitamin alphabet was so comprehensive. Vitamin F is linoleic acid and it is found in omega 6 fatty acids, while vitamin H is biotin (also more commonly known as B7).

The great thing about oil-based products is that don’t require all the emulsifiers, solvents and preservatives that go into creams. So there’s nothing to dislike here except for a dab of phenoxyethanol. And there is so, so much to love. This is really the best vitamin C product I have used and I’ll be buying a replacement for sure. Although given that a little goes a long way, that will be some time off. Just remember, if you follow me in giving Dr. Dennis Gross Triple C Peptide Firming Oil a try, that it should be applied sparingly and left for a minute or two before layering any other products above it.

  • November 8, 2017

    by Marta Wohrle

    Hi Robin, oils would always go after a water-based serum as oils can prevent/ slow down the absorption of another product. I haven't tried it on Firewall as I tend to use it alone at night, so you'll have to experiment. Glad you love it though - so do I!

  • November 5, 2017

    by robin makki

    I love this product. I use about 3 full drops on my neck/chest and 3 delicate drops on my face every morning. Absorbs beautifully, and 1 bottle lasts several months. My skin leans dry, but given that this is an oil, I thought that it would be hydrating? Not a complaint, just an observation that I still need a hydrator.

    Now to my questions, I would like to add Medik8 Firewall to my morning routine ... I would imagine that Firewall would go first, and then the Triple C oil??? Does this oil play nice with other serums and products??? Thanks

  • November 5, 2015

    by Gaye

    I've been reading TIA for a few years now, and have even ordered recommended products, but have never dared to try any product for a review. I have been skincare-obsessed since high school and now, being 52, have tried more than my share of products. Vitamin C is the one ingredient which has not played nice with my skin. I would LOVE to find a facial product containing Vitamin C which agreed with my skin, since it has so much to offer, especially for anti-aging. Thank you for an opportunity to contribute to your very informative website!

  • October 27, 2015

    by Kimberly

    (5 out of 5)

    I tested and reviewed this product for TIA, and loved it. I am on my second bottle now, and the results are as described in Marta's review and mine. One thing I did omit in my review were the results I noticed from the Vitamin K (I assume). I have a few small spider veins on my left cheek which have never gone away with the use of any other product. However, this oil helped the spider veins so much that I no longer need to add concealer to those areas. This is staying in my skincare regimen!

  • September 23, 2015

    by Debbie Slack

    I’d love to try ! I’ve used many oils but never one with vitamin C . I love to use oils on my whole body in the winter my skin drys out terribly in the cold winter months.

  • September 22, 2015

    by Kim

    I have recently found this website and I love it! I have not tried any products by Dr Dennis Gross yet. This oil might be a good one to try in the winter. I can't wait to try to peel and I would also love to try the antioxidant wipes.

  • September 22, 2015

    by Sunnymay

    Vitamin C serum is one of the cornerstones of anti-aging products. Liplines start to become prominent after 45.

  • September 1, 2015

    by Dennis

    Marta, you saying that this is the best vitamin C serum you have tried is kind of a big deal. I'm sold.

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