It comes the time for Truth In Aging's Five Best Anti-Aging Serums of 2013. I’m always excited to see that we have made more new discoveries. This list of anti-aging serum recommendations brings together the most potent and effective.

As always, know that your dollars go toward the highest ratio of active ingredients rather than on marketing, packaging or fillers. These anti-aging serums really work. Watch this video for more details about how I picked the Five Best Anti-Aging Serums of 2013.

  • Medik8 Firewall

    Medik8 Firewall ($145 in the shop). Back in 2009, I got over my initial skepticism about a new serum with copper peptides that had come my way and wrote: It really works. It really, really works. It took four years for Medik8 to get back on my radar and when I tried it again this year, I was not disappointed. Medik8 Firewall is an excellent anti-aging serum that noticeably firms my skin and smooths wrinkles. It is one of the few good copper peptide (a proven wound healer) serums on the market. Copper peptides are given a significant boost by another peptide complex, Matrixyl 3000. Also on the of-high-interest list are cysteine, which helps synthesize glutathione, one of the body’s most important natural antioxidants and detoxifiers, and a powerful free radical scavenger Liprochroman-6.

  • E'shee Clinical Esthetic Elixir of Life KI Therapy Serum

    E'shee Clinical Esthetic Elixir of Life KI Therapy Serum ($189 in the shop). I am on my fourth bottle of E’shee KI Therapy Serum since I first encountered it about 14 months ago (note: in order to walk the talk, I have paid for each one full price). This serum is extremely compatible with my skin and over the course of a year (with a few interruptions for other tests), my skin’s texture has improved so much that people who haven’t seen me for a while ask me if I have had peels (I have not). One of the key actives is Far Infrared (FIR) Ceramic Powder. FIR regenerates collagen and may activate TGF-β1 growth factors. Talking over growth factors, KI also contains E’shee’s signature FGF peptide.

  • BRAD Biophotonic Essential Elixir Multi-Peptide

    BRAD Biophotonic Essential Elixir Multi-Peptide ($95 in the shop). One of our Top 10 for under $100, this serum is packed with amino acids. I tend to use E’shee KI in the mornings and BRAD Multi-peptide at night, waking up to soft and refreshed skin. This serum promises to “restructure, purify, nourish, and re-energize.” And I really couldn’t put it better myself. I am on my second (rather smart, made of Myron glass) bottle and I know they’ll be a third.

  • Your Best Face Control

    Your Best Face Control ($160 in the shop). YBF Control deservedly remains on the Five Best list after being selected for one of last year’s anti-aging serums. While keeping the skin refreshed and moisturized, it really comes into its own in the battle against loss of elasticity. A key ingredient is Syn-Hycan and it does battle against sagging skin and double chins. Another (with a similar function) is Relistase. Plus there’s old favorites such as Matrixyl 3000 and the radical scavengers liprochroman-6 and spin trap.

  • La Vie Celeste Éclairage Restorative Serum

    La Vie Celeste Éclairage Restorative Serum ($98.50 in the shop). La Vie Celeste has made ChroNOline a signature ingredient and it can be found in the line’s latest serum. One of the most promising new actives of the past couple of years, ChroNOline is based on a peptide that beefs up laminin 5, which is like the skin’s scaffolding keeping the epidermis adhered to the dermis, and collagen. Eclairage is also a skin brightener with alpha arbutin and a peptide called B-white. As always with LVC, there are no nasties and tons of natural do-good ingredients.