Free shipping on all orders over $39
My Cart 0 $0.00

You have no items in your shopping cart.

Problems Adding to Cart? Click here for assistance.

iS Clinical Youth Serum

by iS Clinical

iS Clinical Youth Serum
You could receive 25 Points for writing a review and/or rating this product.
SALE $ 150.00 $ 119.00

Free Domestic Shipping Over $39

+ Add to Compare   + Add to Wishlist

Size: 1 oz (30 ml)

iS Clinical Youth Serum has been especially formulated to fight the two main signs of aging: wrinkles and loss of elasticity. With cutting-edge proteins and growth factors that immediately identify and target areas of your complexion that need the most repair, Youth Serum works instantly and effectively to turn back the clock on your complexion. Our community of unbiased men and women just like you tested this serum for over 30 days and saw real results, so you can try it yourself knowing it'll work.

Youth Serum's dynamic duo of patented Extremozymes and copper tripeptide growth factors reconstruct damaged skin for younger, healthier skin; each powerful active encourages skin cells to repair themselves and operate like young cells. A formidable lineup of antioxidants and vitamins ensures that skin is protected from further environmental damage, without the use of parabens.

Tested for 30 days and recommended by Gloria:
iS Clinical Youth Serum is a product that I am thrilled to have tried. The ingredients in this serum are quite the mix. It has plenty of peptides and bio-identical growth factors. Some of their key ingredients are copper tripeptide growth factor and a vitamin, A, C, & E blend. They have a patented Extremozyme technology that provides UV photo protection and prevents environmental damage. I also notice caffeine in the mix which I have used in other products which helps in the reduction of puffiness under the eyes.

After using the product a few days I realized I could not use it under the eye or around the eye. It was a little drying and I saw the signs of milia developing under the eye, and the eyebrow area was flaky. I did use it on the rest of my face and as far up as my cheek bone under the eye down to the décolleté area. After applying the product I noticed that it does have a slight tightening effect which is nice. My skin felt extremely soft and smooth. It has been a good 5 weeks and I actually think my skin looks tighter. I think with continued use it will get even better. My skin felt hydrated and I didn’t use a moisturizer afterwards, only sunscreen. Being that I am almost 56 years old that says a lot to me.

I would say in 5 weeks I am impressed with the results and the packaging is nice as well. The serum is a nice consistency and comes in a dropper form. There is more than enough in 1 dropper to do my whole face and neck and probably a half for the décolleté area. I only used the serum in the morning and I still have some left after five weeks. It is a bit pricey, but I for one am not shy from paying $150 for a great serum that does exactly what it says it will do. So I would say that iS Clinical Youth Serum would be on my list to definitely try. I am not sure yet on where it stands next to my favorite, Medik8 Firewall, but I would certainly say it is in the running for the top spot. I will continue on using this serum until it is gone and see what happens.

Discount codes cannot be applied to this product.
Got Questions? Contact Us
… More
  • Benefits:
    fights free radicals, paraben-free, reduces fine lines, reduces wrinkles, tightens skin

Our Take...

iS Clinical Youth Serum ($150) is a product that I am thrilled to have tried. The ingredients in this serum are quite the mix. It has plenty of peptides and bio-identical growth factors. Some of their key ingredients are copper tripeptide growth factor and a vitamin, A, C, & E blend. They have a... Read Full Article

Your Take...

  • 5 stars 1 out of 5

    I am 41 and I regularly read this site, which I love very much and I was very surprised when I read this review. Also, I am very cautious when buying serums and creams, I do not buy because ads or hype, but this is a total failure. I don't recomend this!
    I read a lot about this serum and ingredients in it, that's why I decided to buy it, but I still can not believe that all of these ingredients can be so ineffective. Of course, I'm angry because of the for nothing spent $ 150. My skin is very responsive and it never really happened that a product does not any effect on my skin. Zero hydration, not a bit of firming and zero effect on wrinkles.
    The texture of this serum is very comfortable, has no odor, but it is completely irrelevant, because it does not give any results. I have not experienced this even with cheap products from the drug store or grocery store. All of the listed ingredients could be lie (I do not own chemical laboratory to analyze this product) or formulation is so bad that does not deliver any results.
    Unfortunately, this serum was not my only purchase. I bought Super Serum Advance +, which was the same.. nothing. Medik8 CE-thione is at least 1000 times more effective vitamin C serum. IS CLINICAL Super Serum Advance is just like plain water, I had also zero effect on my skin.
    After this experience with the two top products of this brand, I think I'll avoid IS CLINICAL.

  • Hi Phyllis, there is a link to our returns policy at the foot of every page:

  • is there a money back guarantee

  • 5 stars 4 out of 5

    I purchased this serum and definitely like the instant firming effects.

Write Your Own Review

You're reviewing: iS Clinical Youth Serum

  • Perfect Good OK Didn't like it Hated it Rate Me
8 + 6 =

* Required Fields

  • December 7, 2015

    by Marta

    Hi Shalini, I would suggest doing some more reading around fibroblasts. They are types of cells that produce collagen, but not only for scars or wound healing. Fibroblasts maintain structural integrity within the connective tissue. While collagen does form scars, that isn't all it does. Collagen is the most abundant protein in the body and fibroblasts make many different types of collagen. Therefore, an active ingredient that helps boost collagen foes not have to cause an injury to work. Some kinds of procedures do work like this, for example laser. But this is not how copper peptides work. You can read more about copper peptides here:

  • December 7, 2015

    5 stars 3 out of 5

    by Shalini Kewalramani

    I purchased this serum and definitely like the instant firming effects. Now it says it contains copper tripeptide growth factors. I need to understand if this is related to Fibroblasts or increases fibroblasts in skin? I came across this article that talks about Fibroblasts and need to understand if :
    1. Is it safe to use this serum daily without cause any harm to skin? (as mentioned in the article below)
    2. For what age group is this serum recommended for

    An excerpt from an article written by a plastic surgeon:
    Collagen has many function but is essentially a space occupying grout-like material between cells. As we get older, the PROPORTION of different types of Collagen in and under our skin as well as the quantity of total collagen change. Some of the collagen is changeable but a lot of it, despite everything you read out there, is NOT.
    The same cells producing collagen, fibroblasts, ALSO produce a LOT of collagen when they lay down scar tissue, whose major component is collagen.

    Whenever someone glowingly encourages you to use PRODUCT X which Stimulates fibroblasts (ie scar cells) to deposit collagen, in effect they are saying, that Product X causes an injury to the skin which cases fibroblast scar cells to react and produce a mild, scar-like collagen formation. With time, this collagen is either broken down completely or is replaced with other mature collagen. Injury = Collagen deposition. Greater injury = greater Collagen deposition = scar tissue. The key with all such treatments is to not over-do the injury to prevent scar formation.

    Either way, it is always better to understand the science behind the hype and take care not to hurt yourself with such products.

  • October 7, 2015

    by Preksha @ TIA

    Hi Gloria,
    Unfortunately this item sold out over the weekend, however we expect more in the coming week. Please note iS Clinical is excluded from discounts as per manufacturer's instructions.

    I'm happy to alert you once it is available again!

  • October 7, 2015

    by Gloria Gerber

    Love this serum. Was hoping to order more but I see it is out of stock! I have to say it is one of the best ones I have tried and truly helps with sagging and wrinkles. After using it only once a day it made a difference in my skin so I will try it twice a day next and see where that leads!

  • October 7, 2015

    5 stars 5 out of 5

    by Gloria Gerber

    I have finished the product and I am thrilled with the results. I am disappointed to see the store is out stock. I will definitely be ordering more of this. It is worth the big price, but any fantastic serum that addresses sagging is in my book. I see it is part of the sale for today.

Water, PVP, Caffeine, Glycerin, Disodium EDTA, Hydroxyethylcellulose, Ceratonia Siliqua (Locust Bean) Gum, Hydrolyzed Casein, Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Butylene Glycol, Xanthan Gum, Carbomer, Triethanolamine, Caprylyl Glycol, Phenoxyethanol, Ahnfeltia Concinna Extract, Beta Vulgaris (Beet) Root Extract [Extrait de racine de betterave], Haberlea Rhodopensis Leaf Extract, Faex (Yeast) Extract [Extrait de levure], Acetyl Tyrosine, Proline, Hydrolyzed Vegetable Protein, AdenosineTriphosphate, Ergothioneine, Saccharide Isomerate, Hydrolyzed Wheat Protein/PVP Crosspolymer, VP/Dimethylaminoethylmethacrylate
Copolymer, Phospholipids, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Asiaticoside, Asiatic Acid, Madecassic Acid, 1,2-Hexanediol
After moisturizer, apply one drop to skin, smoothing around eyes, face and/or neck.
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More